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Document type
monografie, knihy
monografie, knihy
Document record
Source: katalogy Medvik
Title
Estimating COVID-19 vaccine effectiveness against severe acute respiratory infections (SARI) hospitalisations associated with laboratory-confirmed SARS-CoV-2 : an evaluation using the test-negative design : guidance document
Author
Světová zdravotnická organizace. Regionální úřadovna pro Evropu
Date of issue
2021
Publisher
©2021
Copenhagen : World Health Organization, Regional Office for Europe, [2021]
Physical description
52 stran
Language
angličtina
Country
Dánsko
Document type
monografie, knihy
Link
Call number
NLK: online
Record number
MED00207597
Persistent link
Abstract
This guidance document outlines an approach to leverage existing surveillance systems for Severe Acute Respiratory Infection (‎SARI)‎ to estimate COVID-19 vaccine effectiveness (‎VE)‎ in preventing SARI associated with laboratory-confirmed SARS-CoV-2 using existing SARI surveillance systems. The approach uses the test-negative design to evaluate VE; cases are SARI patients who tested positive for SARS-CoV-2, and controls are SARI patients who tested negative for SARS-CoV-2.This document is intended to be used as a guidance document to support countries and institutions that are interested in conducting research on COVID-19 vaccine effectiveness in SARI patients. It outlines an approach to post-introduction COVID-19 vaccine effectiveness evaluation in SARI patients that complements existing WHO Unity Studies, which focus on sero-epidemiological investigations. Research should be conducted only after site-specific protocols are developed and approved by the relevant local ethical review committee(‎s)‎.
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